For me, this song was always the "comfort/reassurance" song that's been with me all of my life.
When I first came to the US, Boston rock music was some of the first contemporary American music I'd heard (along with the 50's/60's music my mom and dad liked) as disco was just being replaced by New Wave. Later on, in middle school my older brother's 'rocker' friends took me under their influential (and probably bad-influence) wing and got me into American classic rock, and then in high school Boston's "Third Stage" album.
So impressed with it, I looked up their older stuff on my own, and fell madly in love with their second album (which oddly Tom Scholz hated the most!) "Don't Look Back" was the first CD I ever bought, before I even had a CD player! LOL
I'd play my cassette version over and over and even got paint on it when I'd stay up and paint my mom's house one summer, and the ink rubbed off of it because I'd play it all the time. ^^
I loved the album so much, but this song always stayed with me, on a personal level.
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It's always reassured me that things will work out in the end, no matter what happens in my life. It means to me that even if I have to go things alone, I'll be all right. It means to me that if things don't always go right in my life, I can do what I can on my end to see them end gracefully and amicably--and that there's something better out there, just waiting if I keep trying... :)
/nostalgia off